AI Agents and DeSci: The Rise and Development of Emerging Hotspots

In the past six months, there has been an emerging wave in the market regarding AI Agents and DeSci. From a narrative perspective, AI Agents focus on their tremendous potential in autonomous decision-making, data analysis, and task execution, adept at solving problems through algorithms; whereas DeSci is dedicated to breaking the traditional barriers of scientific research through blockchain technology, achieving data sharing and transparency, and promoting decentralized knowledge sharing and research funding. This article will summarize the currently prominent and promising tokens related to AI Agents and DeSci.

1. AI Agent: The Rise of Intelligent Systems

1.1 Overview of AI Agent

An AI Agent is an intelligent system that possesses autonomy and goal orientation, capable of perceiving the environment, planning actions, executing tasks, and learning from experience to improve, achieving specific goals without human intervention, such as automatically monitoring data, analyzing anomalies, and making corresponding decisions. Its key characteristics are autonomy and goal orientation.

According to data platform statistics, the current trend of AI is similar to the early stages of the DeFi craze in 2020-2021. Some organizations have also proposed ideas for AI Agents in 2025: AI agents will need independent wallets; decentralized autonomous chatbots; with the widespread use of artificial intelligence, there will be a greater need for unique proofs of different AI personas.

1.2 Popular Token Review

Here are some popular AI Agent related tokens:

• AIXBT: Market cap of $550 million, mental share of 20.7%. Tracks hot discussions on crypto Twitter to identify strong narratives.
• Virtuals: Market cap of $4 billion, mental share of 20.7%. Designed the initial token issuance (IAO) model, users can lock $VIRTUAL to generate new AI agents.
• AI16Z: Market cap of $2 billion, mental share of 8.57%. Permissionless DAO, holding ai16z and degenai tokens.
• Fartcoin: Market cap of $900 million, mental share of 6.93%. A meme coin in the Solana ecosystem, users submit fart jokes to earn tokens.
• Zerebro: Market cap of $560 million, mind share of 4.36%. Autonomous AI agent focused on artistic creation and content generation.
• Griffain: Market cap of $380 million, mind share of 3.53%. An AI Agent based on Solana that simplifies user interaction with cryptocurrencies.
• SNAI: Market value of $83 million, mind share of 1.95%. The token of the cloud server protocol SwarmNode.ai proxy platform.
• GOAT: Market cap of $560 million, mental share of 1.91%. A Meme coin fine-tuned by an artificial intelligence platform.
• ARC: Market value of 300 million USD, mental share of 1.89%. Represents the concept of AI infrastructure.
• TRISIG: Market cap of $74 million, mental share of 1.47%. Claims to be a crypto analyst capable of identifying early alpha projects.

1.3 Trends in AI Agent Development

The current AI Agent craze in on-chain data shows a similar trend to the pre-2020-2021 DeFi explosion, but the current blockchain + AI is still struggling to create the waves of an AI Summer. From an on-chain perspective, Base and Solana have become the main battlegrounds, where high performance and high speculation are key to supporting AI Agents.

The AI project directions worth paying attention to include computing power, infrastructure, memes, launch platforms, and applications. The practical application of AI agents in data analysis is more valuable, such as analyzing on-chain and market data to predict policy trends.

The data transparency of blockchain provides a solid foundation for the development of AI. The on-chain opportunities for AI Agents include both short-term speculation and show hope for the future application of blockchain + AI. Market speculation expectations are mainly reflected in:

1. The continuous rise of AI16Z drives the overall market sentiment of AI Agents;
2. The AI Agent project has evolved from manual to automated.
3. Class AIXBT Twitter analysis tools provide investors with new perspectives;
4. Virtuals achieved success through a model similar to Pump.fun;
5. AI virtual humans and AI works open up new markets in non-cryptocurrency fields, enhancing the breaking the circle effect.

2. DeSci: A New Paradigm for Scientific Innovation

2.1 Overview of DeSci

DeSci( decentralized science) is a model for building a fair and equitable scientific research infrastructure through Web3 technology, aimed at addressing issues such as review, funding, intellectual property management, as well as data transparency and review mechanisms in scientific research. It attempts to introduce the speculative nature of cryptocurrencies into the non-speculative field of scientific research.

The concept of DeSci emerged as early as 2021, but it wasn't until recently that a trading platform invested in and launched the BIO Protocol, along with the participation of well-known industry figures in DeSci-themed conferences, that this sector regained market attention.

2.2 Overview of BIO Protocol

BIO Protocol is a decentralized curation and liquidity protocol in the field of ( DeSci ), aimed at providing resource support for scientific research projects and promoting scientific innovation.

The core components of the protocol include BioDAO, a curation system, intellectual property tokenization and liquidity mechanisms, as well as incentive systems. Through multiple rounds of auctions and airdrop programs, the BIO Protocol has built a diverse and highly participatory community, laying the foundation for a decentralized biomedical research network.

Currently, BioDAO:Launch has successfully launched 7 sub-DAOs, with another 3 in development. The launched sub-DAOs include:

• VITA: Focused on early longevity science research
• ATH: Focus on women's reproductive health research and drug development
• GROW: A platform focused on anti-aging drugs and longevity projects
• PSY: Focus on psychedelic scientific research
• HAIR: Committed to solving hair loss issues
• CRYO: Promoting research in the field of cryopreservation
• NEURON: Committed to Brain Health Research

The sub-DAOs under development include Long Covid Labs, QuantumBioDAO, and Curetopia.

2.3 PumpScience platform

PumpScience is a Meme launch platform launched by Molecule DAO, a DeSci platform in the Solana ecosystem, issuing Meme tokens representing pharmaceuticals on Pump.fun. Related conceptual tokens include:

• RIF: stands for Rifampicin, an antibiotic with potential effects on aging.
• URO: Represents uric acid, which helps cells with their "spring cleaning".
• TRACKEDBIO: Committed to improving the translational efficiency of drugs from preclinical research to clinical trials.

2.4 Other Related Projects

• Scihub: Unofficial token that supports open-source research paper websites
• ANTI and PRO: A pair of quantum entangled combination tokens expressing different attitudes towards Meme Tokens.
• WORM: The first on-chain digital brain, simulating the neural network of the beautiful nematode.
• GENOME: A project for gene data monetization, focusing on genomic data.
• GALEON: Innovating electronic health record management using blockchain technology
• DRUGS: Medical and Pharmaceutical Meme Coin, aimed at disrupting traditional large pharmaceutical companies.
• RSC: Tokenized social network that rewards scientists for openly sharing academic content.

Conclusion: The Development Prospects of AI Agents and DeSci

Although both AI Agent and DeSci are primarily driven by memes, their fundamental attributes differ from other meme logics:

1. Fundamental Differences: AI Agent and DeSci are supported by technology, aligning more with the Kondratiev wave cycle of commodity economies.

2. Different methods of breaking the circle: DeSci relies more on external breaking of the circle, requiring specific influential "people"; AI Agent requires internal breaking of the circle, focusing on "usable", "fun", and "valuable".

3. The growth logic of the leading effect is different: DeSci has yet to see a leading project with a market value of 1 billion, and its growth relies more on projects like BIO Protocol; AI Agent, on the other hand, needs to continuously iterate its own entertaining gameplay.

Overall, AI Agent focuses on the value investment trend of blockchain + AI, with stronger potential to break out; DeSci benefits from discussions by industry influencers and the promotion of investment institutions. In an environment with insufficient market innovation, AI Agent and DeSci are expected to become the main points of speculation in this bull market.